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ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS

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| | L6001 ACONITINE
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Neurotoxic; opens the TTX-sensitive Na+ channel in the heart and other tissues; used for creating models of cardiac arrhythmia.
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Alkaloid C34H47NO11 from the plant Aconitum karacolicum, Ranunculaceae.
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| PRICES |
| Quantity | US Dollars | EURO |
50 mg | 92.40 | 66.00 |
250 mg | 369.60 | 264.00 |
- Molecular Weight : 645.33 Da.
- Melting Point : 194-202 °C
- Solubility in : chloroform, benzene; slightly in alcohol, ether; practically not in water.
- Purity min. : 98 %
- Toxicity (LD50) : mice (i.v.): 0.12 mg/kg
rats (orally): 5.97 mg/kg
- Storage recommendations : stable in dry state; store at +4°C, in dark place.
- CAS Reg. No. : 302-27-2
- Merck Index 11th Ed. : 113
- Bibliography :
- Sato et al., "Pharmacological actions of Aconitine alkaloids" Tohoku J. exp. Med. 1979 128:175-187 (1979).
- Muroi et al., Neuropharmacology 29:567 (1990).
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