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Home Page > Alphabetical Index > ACONITINE

ACONITINE Prod. No L6001 - CAS # 302-27-2
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Product Name ACONITINE
(Syn.: Aconitin‚ Aconitinum‚ Aconitysat‚ Akonitin)
Product Code L6001
ACONITINE

C34H47NO11
Molecular Formula C34H47NO11
Description

Neurotoxic; opens the TTX-sensitive Na+ channel in the heart and other tissues; used for creating models of cardiac arrhythmia.

Alkaloid C34H47NO11 ‚ from the plant Aconitum karacolicum‚ Ranunculaceae.
 
Biological Activity

 
Chemical and Physical Properties
 
CAS No. 302-27-2 Molecular Weight 645.33 Da.
RTECS Physical Form
Merck Index No (13th Ed.) 113 Melting point 194-202 °C
PubChem SID 8148149 Solubility chloroform‚ benzene; slightly in alcohol‚ ether; practically not in water.
Purity 98 % Optical Activity
Toxicity (LD50) mice (i.v.): 0.12 mg/kg
rats (orally): 5.97 mg/kg
Chemical Names 20-ethyl-3a‚13‚15a-trihydroxy-1a‚6a‚16ß-trimethoxy-4-(methoxymethyl)aconitane-8‚14a-diyl 8-acetate 14-benzoate
Storage & Reconstitution Recommendations stable in dry state; store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Sato et al., "Pharmacological actions of Aconitine alkaloids" Tohoku J. exp. Med. 1979 128:175-187 (1979).
  2. Muroi et al., Neuropharmacology 29:567 (1990).
 
Prices
Code
Quantity
US $
€uro
L6001
50 mg
92.40
66.00
250 mg
369.60
264.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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