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Home Page > Alphabetical Index > DESOXYPEGANINE HCl

DESOXYPEGANINE HCl Prod. No L6009 - CAS # 61939-05-7
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Product Name DESOXYPEGANINE HCl
Product Code L6009
DESOXYPEGANINE HCl

C11H12N2.HCl .2H2O
Molecular Formula C11H12N2.HCl .2H2O
Description

a substance which inhibits cholinesterases reversibly.

Alkaloid C11H12N2.HCl .2H2O ‚ from plants of the Zygophyllaceae family
 
Biological Activity

inhibits butyrylcholinesterase more strongly than acetylcholinesterase. Desoxypeganine hydrochloride inhibits also monoamine oxydases. Because of the reciprocal interaction‚ a functional balance appears between the cholinergic and adrenergic activities which reduces the toxicity of this substance as regards its anticholinesterase activity.
Desoxypeganine hydrochloride crosses easily the blood-brain barrier.
 
Chemical and Physical Properties
 
CAS No. 61939-05-7 Molecular Weight 244.7 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 255-256 °C.
PubChem SID Solubility dissolves in water‚ in alcohol; slightly in chloroform; not in acetone.
Purity 99.5% (HPLC). Optical Activity
Toxicity (LD50) mice (i.p.): 56 mg/kg.
mice (orally): 98 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations stable in dry state; store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. S.Yu. Yunusov, Alkaloids, FAN, p. 242. Tashkent (1983) (Russian).
  2. N. Tulyaganov and al., Pharmacologia i toxicologia 3:37 (1986) (Russian).
 
Prices
Code
Quantity
US $
€uro
L6009
20 mg
112.00
80.00
100 mg
448.00
320.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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