a cardiac specific inhibitor of the Na⁺/K⁺-ATPase; interferon inducer.

Glycoside C₄₅H₇₄O₁₇ from plants of the Leguminosae family.

• Molecular Weight : 886 Da.
  
  
• Melting Point : 235-236 °C.
  
  
• Solubility in : DMSO, pyridine; not well in water and alcohol.
  
  
• Purity min. : 99.99 % (TLC, mass spectrometry, NMR).
  
  
• Biological Activity : Askendoside D presents a high selectivity for the cardiac Na⁺/K⁺-ATPase, with practically no activity on brain or kidney Na⁺/K⁺-ATPases, as compared with other cardiac glycosides (unpublished); it is also an interferon inducer.
  
  
• Toxicity (LD₅₀) : mice (i.p.): no mortality at 1 000 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 86408-17-5
  
  
• Bibliography :
  
  1. Isaev M.I. et al., Chem.Nat.Comp. (1989). 2:131
  2. Isaev M.I. et al., Chem.Nat.Comp. (1983). 2:170