Nicotinic receptor antagonist, ganglioblocker; presents weak affinity at brain aBungarotoxin-sensitive nAChR.

Alkaloid C₂₅H₄₁NO₇ from plants of the Aconitum genus, Ranunculaceae.

• Molecular Weight : 467 Da.
  
  
• Melting Point : 214-216 °C.
  
  
• Solubility in : chloroform; slightly in methanol, acetone; very slightly in water.
  
  
• Purity min. : 97 % (TLC, mass-spectrometry).
  
  
• Toxicity (LD₅₀) : mice (i.v.): 175 mg/kg. mice (i.p.): 550 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 509-18-2
  
  
• Merck Index 11th Ed. : 2868
  
  
• Bibliography :
  
  1. Skaric et al., J; Amer. Chem. Soc. (1958) 80:4434
  2. Marion, Pure and Applied Chem. (1963) 6(4):621