an anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates.

Quinoline alkaloid C₁₅H₁₇NO₄ from plants of the Rutaceae family.

• Molecular Weight : 275 Da.
  
  
• Melting Point : 127-128 °C.
  
  
• Solubility in : mineral acids, alcohol.
  
  
• Purity min. : 97 % (TLC).
  
  
• Biological Activity : at 150-200 mg/kg: depresses the reaction of orientation of mice; at 150-200 mg/kg: suppresses the convulsant action of strychnine, corazole, caffeine and picrotoxin; at 200-400 mg/kg: depresses the motor-activity of mice and rats; at 300 mg/kg: depresses the conditioned reflex activity of rats; increases the soporific action of ethanol, ether, chloral hydrate and barbiturates.
  
  
• Toxicity (LD₅₀) : mice (s.c.): 970 mg/kg. mice (i.p.): 855 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 22964-77-8
  
  
• Bibliography :
  
  1. Bessonova et al., Chem. Nat. Comp. (1971). 5:626
  2. Polievtsev et al., "About the influence of dubinidine on the CNS." Pharmacology of alkaloids. Tashkent (1965) (Russian).