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Home Page > Alphabetical Index > DUBINIDINE

DUBINIDINE Prod. No L6020 - CAS # 22964-77-8
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Product Name DUBINIDINE
Product Code L6020
DUBINIDINE

C15H17NO4
Molecular Formula C15H17NO4
Description

an anticonvulsant which reduces motor activity‚ enhances the effects of alcohol‚ ether and barbiturates.

Quinoline alkaloid C15H17NO4 ‚ from plants of the Rutaceae family.
 
Biological Activity

at 150-200 mg/kg: depresses the reaction of orientation of mice;
at 150-200 mg/kg: suppresses the convulsant action of strychnine‚ corazole‚ caffeine and picrotoxin;
at 200-400 mg/kg: depresses the motor-activity of mice and rats;
at 300 mg/kg: depresses the conditioned reflex activity of rats;
increases the soporific action of ethanol‚ ether‚ chloral hydrate and barbiturates.
 
Chemical and Physical Properties
 
CAS No. 22964-77-8 Molecular Weight 275 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 127-128 °C.
PubChem SID Solubility mineral acids‚ alcohol.
Purity 97 % (TLC). Optical Activity [a]D - 62.95 (c = 3.56 in ethanol).
Toxicity (LD50) mice (s.c.): 970 mg/kg.
mice (i.p.): 855 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Bessonova et al., Chem. Nat. Comp. (1971). 5:626
  2. Polievtsev et al., "About the influence of dubinidine on the CNS." Pharmacology of alkaloids. Tashkent (1965) (Russian).
 
Prices
Code
Quantity
US $
€uro
L6020
20 mg
112.00
80.00
100 mg
448.00
320.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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