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Home Page > Alphabetical Index > NORFLUOROCURARINE

NORFLUOROCURARINE Prod. No L6025 - CAS # 6880-54-2
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Product Name NORFLUOROCURARINE
(Syn.: Vincanine)
Product Code L6025
NORFLUOROCURARINE

C19H20N2O
Molecular Formula C19H20N2O
Description

a CNS stimulant; convulsant; probably Glycinergic antagonist.

Indole alkaloid C19H20N2O ‚ from the plant Vinca erecta‚ Apocynaceae.
 
Biological Activity

facilitates the neurotransmission at synapses between neurons of the spinal cord. Low concentrations excite the CNS‚ and toxic concentrations cause convulsions leading to mortality. The convulsions look like those caused by Strychnine‚ but Norfluorocurarine is 10 times as potent as Strychnine.
 
Chemical and Physical Properties
 
CAS No. 6880-54-2 Molecular Weight 292 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 187-188 °C.
PubChem SID Solubility chloroform; less in alcohol.
Purity 97 % (TLC). Optical Activity [a]D -992° (c = 1‚39 in methanol)
Toxicity (LD50) ( LD50 using a 0.1% solution):
mice (i.v.): 5.6 mg/kg;
mice (s.c.): 14 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Sultanov et al., "Pharmacology of alkaloids from Vinca erecta Rgl. et Schmalh." Second Indo-Soviet Symposium on the Chemistry of Natural Products Including Pharmacology. New-Delhi (1970) . 38-39
  2. Boit, Ergebnisse der Alkaloid-Chemie bis 1960. Akademie-Verlag, Berlin (1960). p. 623
 
Prices
Code
Quantity
US $
€uro
L6025
20 mg
114.80
82.00
100 mg
574.00
410.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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