FLUOROCURARINE CHLORIDE - LATOXAN Technical Data Sheet
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L6026 FLUOROCURARINE CHLORIDE
( Vincanine chlormethylate )

a short-acting selective sympathetic ganglioblocker, with a weak antagonist activity on the nicotinic receptor at the neuromuscular junction; hypotensive.

Alkaloid C20H23ClN2O derivative of Norfluorocurarine from the plant Vinca erecta, Apocynaceae.


PRICES
QuantityUS DollarsEURO
20 mg 134.40 96.00
100 mg 537.60 384.00


  • Molecular Weight : 342.5 Da.

  • Melting Point : 266-267 °C.

  • Solubility in : well in water and methanol.

  • Purity min. : 97 % (TLC, mass-spectrometry).

  • Biological Activity : Fluorocurarine chloride is a short-acting ganglioblocker. 0.02-0.2 mg/kg selectively block sympathetic ganglia with an activity 6 times as potent as that of arfonad; 2-3 mg/kg block the neuromuscular conductivity by non-depolarizing action. Fluorocurarine chloride is not toxic for the cardiovascular system; it lowers the blood pressure and has no influence on M-cholinergic and histaminergic receptors.

  • Toxicity (LD50) : mice (i.v.): 4.6 mg/kg (solution 0.1%). mice (s.c.): 102.5 mg/kg (solution (1%).

  • Storage recommendations : Store at +4°C, in dark place.

  • CAS Reg. No. : 22273-09-2

  • Bibliography :
    1. Vakhabov. Pharmacol. Toxicol. 1:18 (1976) (Russian).



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    Revised : 26/04/2007 10:27 - Copyright © Latoxan