an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmia caused by electric stimulation of the auricule or by Aconitine.

Quinoline alkaloid C₁₆H₂₁NO₅ from plants of the Rutaceae family.

• Molecular Weight : 307 Da.
  
  
• Melting Point : 137-139 °C.
  
  
• Solubility in : well in water, ethanol and methanol.
  
  
• Purity min. : 96 % (TLC).
  
  
• Biological Activity : >100 mg/kg, in mice, depress the reaction of orientation, decreases the convulsant and lethal action of corazole and strychnine, causes hypothermia; 10-20 mg/kg (i.v.) prevent arrhythmia caused by electric stimulation of the auricule or by Aconitine or CaCl2. increases the action of chloral hydrate.
  
  
• Toxicity (LD₅₀) : mice (i.v.): 61.1 mg/kg. mice (orally): 1 084.0 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 2520-38-9
  
  
• Bibliography :
  
  1. Eskairov et al., Repts. Acad. Sci. UzSSR. 5:23 (1958) (Russian).
  2. Pastukhova et al., Chem. Nat. Comp.1:27 (1965).