Cholinesterase inhibitor; antimyasthenic, nicotinic receptor agonist at the ganglionic and the neuromuscular junctions.

Alkaloid C₁₇H₂₁NO₃.HBr from the plants of Ungernia genus, Amaryllidaceae.

• Molecular Weight : 368.28 Da.
  
  
• Melting Point : 242-252 °C.
  
  
• Solubility in : moderately in water; practically not in 95 % alcohol, chloroform and ether.
  
  
• Purity min. : 97.5% (TLC, mass spectrometry).
  
  
• Toxicity (LD₅₀) : mice (i.p.): 13.7 mg/kg. mice (s.c.): 13.5 mg/kg. mice (i.v.): 4.0 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 1953-04-4
  
  
• Merck Index 11th Ed. : 4245
  
  
• Bibliography :
  
  1. D. H. R. Barton, G. W. Kirby. J. Chem. Soc., 806 (1962); Proc. Chem. Soc. (1960) 392
  2. Holl et al., Electroencephalography Clinical Neurophysiology (1992) 82:445