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Home Page > Alphabetical Index > NUDIKAULINE PERCHLORATE
| NUDIKAULINE PERCHLORATE Prod. No L6037 - CAS # 99815-83-5 |
| Product Name | NUDIKAULINE PERCHLORATE |
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| Product Code | L6037 |  C38H50N2O11.HClO4 |
| Molecular Formula | C38H50N2O11.HClO4 | |
| Description | α-Bungarotoxin neuronal nicotinic receptor antagonist with a selectivity comparable to that of Methyllycaconitine at the brain sites (nanomolar affinity); potent medium-acting non depolarizing neuromuscular blocker; muscle relaxant. Alkaloid C38H50N2O11.HClO4 ‚ from plants of the Ranunculaceae family. |
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| Biological Activity | recent studies (see attached sheet) show that Nudikauline perchlorate acts as neuronal a-Bungarotoxin-sensitive brain nicotinic receptors antagonist‚ with a comparable affinity to Methyllycaconitine. |
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| Chemical and Physical Properties | |||||||||||||||
| CAS No. | 99815-83-5 | Molecular Weight | 810.5 Da. | ||||||||||||
| RTECS | Physical Form | ||||||||||||||
| Merck Index No (13th Ed.) | Melting point | 209-212 °C. | |||||||||||||
| PubChem SID | Solubility | ethanol. | |||||||||||||
| Purity | 96% (TLC‚ mass-spectrometry). | Optical Activity | [a]D +47° (c = 0.42 chloroform). | ||||||||||||
| Toxicity (LD50) | mice (i.v.): 1.8 mg/kg. mice (i.p.): 13.0 mg/kg. mice (orally): 38.0 mg/kg. |
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| Chemical Names | |||||||||||||||
| Storage & Reconstitution Recommendations | Store at +4°C‚ in dark place. | ||||||||||||||
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| External Links |  PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID |
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