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Home Page > Alphabetical Index > NUDIKAULINE PERCHLORATE

NUDIKAULINE PERCHLORATE Prod. No L6037 - CAS # 99815-83-5
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Product Name NUDIKAULINE PERCHLORATE
Product Code L6037
NUDIKAULINE PERCHLORATE

C38H50N2O11.HClO4

Molecular Formula C38H50N2O11.HClO4
Description

α-Bungarotoxin neuronal nicotinic receptor antagonist with a selectivity comparable to that of Methyllycaconitine at the brain sites (nanomolar affinity); potent medium-acting non depolarizing neuromuscular blocker; muscle relaxant.

Alkaloid C38H50N2O11.HClO4 ‚ from plants of the Ranunculaceae family.

 
Biological Activity

recent studies (see attached sheet) show that Nudikauline perchlorate acts as neuronal a-Bungarotoxin-sensitive brain nicotinic receptors antagonist‚ with a comparable affinity to Methyllycaconitine.

 
Chemical and Physical Properties
 
CAS No. 99815-83-5 Molecular Weight 810.5 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 209-212 °C.
PubChem SID Solubility ethanol.
Purity 96% (TLC‚ mass-spectrometry). Optical Activity [a]D +47° (c = 0.42 chloroform).
Toxicity (LD50) mice (i.v.): 1.8 mg/kg.
mice (i.p.): 13.0 mg/kg.
mice (orally): 38.0 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Kulanthaivel et al., Heterocycles (1985). 23:2515
 
Prices
Code
Quantity
US $
€uro
L6037
5 mg
141.40
101.00
25 mg
565.60
404.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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