Ca²⁺ channel blocker; antiplatelet agent; GABA binding activator; antiarrhythmic with complex mechanism of action.

Alkaloid C₂₀H₁₉NO₅.HCl from plants of the Fumariaceae family.

• Molecular Weight : 389.65 Da.
  
  
• Solubility in : slightly in water; practically not in alcohol.
  
  
• Purity min. : 98 %.
  
  
• Biological Activity : 0.1 to 10 µM increase the binding of 3H-GABA with receptors in rat synaptosomes.
  
  
• Toxicity (LD₅₀) : mice (i.v.): 35.5 mg/kg.
  mice (orally): 160 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 6164-47-2
  
  
• Merck Index 11th Ed. : 7912
  
  
• Bibliography :
  
  1. Ko et al., Jap. J. Pharmacol. (1992) 58:1
  2. Kardos et al., Arzneim-Forsch.(1986) 36(6):939-940