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Home Page > Alphabetical Index > PROTOPINE HCl

PROTOPINE HCl Prod. No L6044 - CAS # 6164-47-2
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Product Name PROTOPINE HCl
Product Code L6044
PROTOPINE HCl

C20H19NO5.HCl
Molecular Formula C20H19NO5.HCl
Description

Ca2+ channel blocker; antiplatelet agent; GABA binding activator; antiarrhythmic with complex mechanism of action.

Alkaloid C20H19NO5.HCl ‚ from plants of the Fumariaceae family.
 
Biological Activity

0.1 to 10 µM increase the binding of 3H-GABA with receptors in rat synaptosomes.
 
Chemical and Physical Properties
 
CAS No. 6164-47-2 Molecular Weight 389.65 Da.
RTECS Physical Form
Merck Index No (13th Ed.) 7912 Melting point
PubChem SID Solubility slightly in water; practically not in alcohol.
Purity 98 %. Optical Activity
Toxicity (LD50) mice (i.v.): 35.5 mg/kg.

mice (orally): 160 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Ko et al., Jap. J. Pharmacol. (1992) 58:1
  2. Kardos et al., Arzneim-Forsch.(1986) 36(6):939-940
 
Prices
Code
Quantity
US $
€uro
L6044
5 mg
127.40
91.00
25 mg
509.60
364.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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