a sedative and anticonvulsant; causes hypothermia; estrogenic activity.

Quinoline alkaloid C₁₄H₁₃NO₄ from plants of the Rutaceae family.

• Molecular Weight : 259 Da.
  
  
• Melting Point : 172-173°C.
  
  
• Solubility in : 10 % HCl; not in water.
  
  
• Purity min. : 98 % (TLC, NMR).
  
  
• Biological Activity : 100-300 mg/kg orally inhibit motor-activity, decrease the excitatory action of Phenamine and Caffeine, decrease the convulsant action of Corazole and Strychnine, increase the action of soporifics, lower the body temperature and inhibit provoked aggressiveness. estrogenic activity at 30-50 mg/kg during 3 days.
  
  
• Toxicity (LD₅₀) : mice (i.p.): 160 mg/kg. mice (s.c.): more than 600 mg/kg. mice (orally): more than 1 000 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• CAS Reg. No. : 83-95-4
  
  
• Merck Index 11th Ed. : 1354
  
  
• Bibliography :
  
  1. Asahina et al., Ber. (1930). 63:2052
  2. Moyse-Mignon, Ann. Pharm. Franc. (1947). 5:410