HETISINE HYDROCHLORIDE - LATOXAN Technical Data Sheet
ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS
L6053 HETISINE HYDROCHLORIDE
a potent antiarrhytmic and local anesthetic.
Alkaloid C20H27NO3.HCl from plants of the Ranunculaceae family.
PRICES
Quantity
US Dollars
EURO
10 mg
141.40
101.00
50 mg
565.60
404.00
Molecular Weight : 365 Da.
Melting Point : 290 °C. (decomp.)
Solubility in : water; not well in ethanol and methanol.
Purity min. : 97 % (TLC, mass spectrometry).
Biological Activity : the dosage for antiarrhythmic activity in mammals ranges from 0.1 to 1.0 mg/kg and is the most effective in arrythmias caused by calcium chloride (200-250 mg/kg).
ED50 for antifibrillatory activity in rat is 0.15 mg/kg.
Toxicity (LD50) : mice (i.v.): 26.2 mg/kg.
Storage recommendations : Store at +4°C, in dark place.
CAS Reg. No. : 149926-20-5
Bibliography :
Pelletier et al., Phytochemistry (1968). 7:625-635