an antiarrhythmic; fast inward Na⁺ current blocker.

C₁₉-diterpenoid alkaloid C₂₇H₄₁NO₈ from plants of the Ranunculaceae family.

• Molecular Weight : 507 Da.
  
  
• Melting Point : 185-187 °C.
  
  
• Solubility in : freely in chloroform, methanol; less in acetone, ethanol.
  
  
• Purity min. : 97 % (TLC, mass spectrometry).
  
  
• Biological Activity : Deltaline is 2-2.5 times more active than quinidine and less toxic than this alkaloid. The effective antiarrhythmic dosage intravenously in mammals (rats, cats, dogs) is 10-15 mg/kg.
  
  
• Toxicity (LD₅₀) : mice (i.v.):130 mg/kg. rats (i.v.):136 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place
  
  
• CAS Reg. No. : 6836-11-9
  
  
• Bibliography :
  
  1. Carmack et al., J. Am. Chem. Soc.(1958) 80:497
  2. Pelletier et al., J. Am. Chem. Soc.(1981) 103:6536