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Home Page > Alphabetical Index > DELTALINE

DELTALINE Prod. No L6057 - CAS # 6836-11-9
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Product Name DELTALINE
(Syn.: Eldeline)
Product Code L6057
DELTALINE

C27H41NO8
Molecular Formula C27H41NO8
Description

an antiarrhythmic; fast inward Na+ current blocker.

C19-diterpenoid alkaloid C27H41NO8 ‚ from plants of the Ranunculaceae family.
 
Biological Activity

Deltaline is 2-2.5 times more active than quinidine and less toxic than this alkaloid.
The effective antiarrhythmic dosage intravenously in mammals (rats‚ cats‚ dogs) is 10-15 mg/kg.
 
Chemical and Physical Properties
 
CAS No. 6836-11-9 Molecular Weight 507 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 185-187 °C.
PubChem SID Solubility freely in chloroform‚ methanol; less in acetone‚ ethanol.
Purity 97 % (TLC‚ mass spectrometry). Optical Activity
Toxicity (LD50) mice (i.v.):130 mg/kg.
rats (i.v.):136 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place
Safety Recommendations
 
Bibliographic References
  1. Carmack et al., J. Am. Chem. Soc.(1958) 80:497
  2. Pelletier et al., J. Am. Chem. Soc.(1981) 103:6536
 
Prices
Code
Quantity
US $
€uro
L6057
100 mg
142.80
102.00
500 mg
571.20
408.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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