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Home Page > Alphabetical Index > EUDESMINE

EUDESMINE Prod. No L6060 - CAS # 526-06-7
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Product Name EUDESMINE
Product Code L6060
EUDESMINE

C22H26O6
Molecular Formula C22H26O6
Description

a substance presenting an estrogenic activity and sedative effects.

Lignan C22H26O6 ‚ from plants of the Rutaceae family.
 
Biological Activity

Eudesmine presents a short acting estrogenic activity and a sedative effect.
- 1.5 and 10 mg/kg cause a mass increase of the uterus in non-pubescent rats and induces oestrus in ovarectomized pubescent rats.
- 50 and 100 mg/kg cause a general relaxation of the animals and extends by 2.5 times the effects of soporifics.
- 100‚ 200 and 500 mg/kg present no effect on the convulsant activity of Caffeine (300 mg/kg)‚ Corazole (Pentylenetrazole) (75 mg/kg) and Strychnine (1 mg/kg).
 
Chemical and Physical Properties
 
CAS No. 526-06-7 Molecular Weight 386 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 107-108 °C.
PubChem SID Solubility chloroform; very slightly in alcohol and acetone; not in water.
Purity 97 % (TLC). Optical Activity 20
[a]D +60.5° (c = 2.38 in acetone).
Toxicity (LD50) mice (orally): 1 900 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Whiting. Natural Products Reports (1985). 2:195
  2. Atal et al., Am. Journ. Chem. Soc. (1967). (c) 2228
 
Prices
Code
Quantity
US $
€uro
L6060
10 mg
134.40
96.00
50 mg
537.60
384.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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