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ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS

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| | L6067 LEUCOMISINE
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an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
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Sesquiterpene lactone C15H18O3 from plants of the Compositae family.
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| PRICES |
| Quantity | US Dollars | EURO |
100 mg | 152.60 | 109.00 |
500 mg | 610.40 | 436.00 |
- Molecular Weight : 246 Da.
- Melting Point : 199-200 °C.
- Solubility in : chloroform, acetone, ethylacetate, benzole; not in water.
- Purity min. : 98 % (TLC, mass spectrometry).
- Biological Activity : 1 mg/kg during 90 days, decrease the size and thickness of atherosclerotic discs, the amount of foam cells and the cholesterol content in aorta of rabbits fed with high cholesterol level diet.
It also reduces the permeability increase of aorta and microvessels for high molecular weight albumin-Blue Evans complex caused by Cholesterol, Bradykinin, Ovalbumin or Histamine.
In blood serum and in liver, Leucomisine also presents an hypolipidemic activity on all major lipid classes, especially esters of cholesterols.
- Toxicity (LD50) : mice (orally): 5 000 mg/kg.
- Storage recommendations : Store at +4°C, in dark place.
- CAS Reg. No. : 17946-87-1
- Bibliography :
- Rybalko. J. obsh. Khimiya (1963)(Russian) 33(8):2734
- Kurmukov et al., Pharmacol. Toxicol. (1991) (Russian). 54(3):35-37
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Revised : 26/04/2007 10:27 - Copyright © Latoxan |
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