NITRARINE DIHYDROCHLORIDE - LATOXAN Technical Data Sheet
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L6068 NITRARINE DIHYDROCHLORIDE

a hypotensive, spasmolytic, coronary dilator, sedative in experimental arrhythmias.

Alkaloid C20H25N3.2HCl from plants of the Zygophyllaceae family.


PRICES
QuantityUS DollarsEURO
50 mg 100.80 72.00
250 mg 403.20 288.00


  • Molecular Weight : 380 Da.

  • Melting Point : 265-266 °C.

  • Solubility in : well in water, methanol and ethanol.

  • Purity min. : 97 %.

  • Biological Activity : in experimental arrhythmias in the cat, caused by calcium chloride, Aconitine and electric cardiac stimulation, Nitrarine dihydrochloride presents a hypotensive, spasmolytic, coronary dilating and sedative action. Its antiarrhythmic properties are due to its stabilizating effects on the membrane and its coronary dilating action. Nitrarine dihydrochloride is 3-4 times as potent as Novocainamide and Quinidine, and the duration of its effect is 2-5 times longer than that of these products.

  • Toxicity (LD50) : mice (i.v.): 117 mg/kg (1 % solution). mice (underdermally): 520 mg/kg (2 % solution).

  • Storage recommendations : Store at +4°C, in dark place.

  • CAS Reg. No. : 20069-05-0

  • Bibliography :
    1. Nasirov et al. Chem. Nat. Comp. (1976). 3:334-345
    2. Aminov et al. Chem. Pharm. J. (1991) (Russian). 3:56-58



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    Revised : 26/04/2007 10:27 - Copyright © Latoxan