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Home Page > Alphabetical Index > NITRARINE DIHYDROCHLORIDE
| NITRARINE DIHYDROCHLORIDE Prod. No L6068 - CAS # 20069-05-0 |
| Product Name | NITRARINE DIHYDROCHLORIDE |
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| Product Code | L6068 |  C20H25N3.2HCl |
| Molecular Formula | C20H25N3.2HCl | |
| Description | a hypotensive‚ spasmolytic‚ coronary dilator‚ sedative in experimental arrhythmias. Alkaloid C20H25N3.2HCl ‚ from plants of the Zygophyllaceae family. |
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| Biological Activity | in experimental arrhythmias in the cat‚ caused by calcium chloride‚ Aconitine and electric cardiac stimulation‚ Nitrarine dihydrochloride presents a hypotensive‚ spasmolytic‚ coronary dilating and sedative action. Its antiarrhythmic properties are due to its stabilizating effects on the membrane and its coronary dilating action. Nitrarine dihydrochloride is 3-4 times as potent as Novocainamide and Quinidine‚ and the duration of its effect is 2-5 times longer than that of these products. |
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| Chemical and Physical Properties | |||||||||||||||
| CAS No. | 20069-05-0 | Molecular Weight | 380 Da. | ||||||||||||
| RTECS | Physical Form | ||||||||||||||
| Merck Index No (13th Ed.) | Melting point | 265-266 °C. | |||||||||||||
| PubChem SID | Solubility | well in water‚ methanol and ethanol. | |||||||||||||
| Purity | 97 %. | Optical Activity | |||||||||||||
| Toxicity (LD50) | mice (i.v.): 117 mg/kg (1 % solution). mice (underdermally): 520 mg/kg (2 % solution). |
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| Storage & Reconstitution Recommendations | Store at +4°C‚ in dark place. | ||||||||||||||
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| External Links |  PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID |
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