an adrenergic blocker in the central and peripheral nervous systems; hypotensive and sedative; increases the effect of hypnotics and analgesics.

Amaryllidaceae alkaloid C₁₈H₂₁O₅N from plants of the Ungernia genus, Amaryllidaceae.

• Molecular Weight : 331 Da.
  
  
• Melting Point : 173-174 °C.
  
  
• Solubility in : chloroform; not well in alcohol.
  
  
• Purity min. : 98 % (TLC, mass spectrometry).
  
  
• Biological Activity : Unsevine acts directly on the CNS, inhibits the reaction of orientation, prolongs the action of soporifics, enhances the effects of analgesics and prevents convulsions. Possesses a central and peripheral Adrenoblocking activity; hypotensive.
  
  
• Toxicity (LD₅₀) : mice (i.v.): 171.5 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place; solution for experiments: 0.5% to 1%.
  
  
• CAS Reg. No. : 4838-99-7
  
  
• Bibliography :
  
  1. Zakirov et al., Repts. Acad. Sci. UzSSR (1966) (Russian). 6:34