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Home Page > Alphabetical Index > SEVEDINDIONE

SEVEDINDIONE Prod. No L6082 - CAS #
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Product Name SEVEDINDIONE
Product Code L6082
SEVEDINDIONE

C27H41NO3
Molecular Formula C27H41NO3
Description

antiarrhythmic‚ belonging to a novel structural class of antiarrhythmics.

Steroid alkaloid C27H41NO3 ‚ from plants of the Liliaceae family.
 
Biological Activity

Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine. The effective dose on rats and dogs is 3-10 mg/kg. In some experiments‚ it can be observed an increase of the hypotensive activity due to vagal nerve stimulation during 30-90 mn.
 
Chemical and Physical Properties
 
CAS No. Molecular Weight 427 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 215-217 °C.
PubChem SID Solubility well in ethanol and chloroform.
Purity 95 % (TLC‚ mass spectrometry‚ NMR). Optical Activity
Toxicity (LD50) mice (i.v.): 235 mg/kg (194-284).
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place; recommended concentration in aqueous solution: 10-5 to 10-2 g/ml.
Safety Recommendations
 
Bibliographic References
  1. Samikov et al., Chem. Nat. Comp. (1977). 5:673
 
Prices
Code
Quantity
US $
€uro
L6082
5 mg
72.80
52.00
25 mg
291.20
208.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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