an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator.

Tropane alkaloid C₁₇H₂₃NO₄ from plants of the Convolvulaceae family.

• Molecular Weight : 305 Da.
  
  
• Melting Point : 114-115 °C.
  
  
• Solubility in : acetone, ethanol, DMSO.
  
  
• Purity min. : 97 % (TLC, mass spectrometry).
  
  
• Biological Activity : Convolamine presents an anesthetic acting on the nerve endings with a lower activity level than that of Convolvine. a 2 % solution lowers the sensitive nerve fibers conductivity with a much higher and longer activity as compared with the effect on motor nerve fibers. As with Convolvine, Convolamine (1/1000 to 1/3000) inhibits cardiac activity, dilates the vessels from isolated ear of rabbit; at 3 mg/kg, lowers the arterial pressure in decerebrated cats.
  
  
• Toxicity (LD₅₀) : mice (s.c.):25-30 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.Solution for use: 0.1 - 2 %.
  
  
• CAS Reg. No. : 500-56-1
  
  
• Bibliography :
  
  1. Oreckov et al., Ber (1934). 67:52