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Home Page > Alphabetical Index > CONVOLAMINE

CONVOLAMINE Prod. No L6086 - CAS # 500-56-1
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Product Name CONVOLAMINE
(Syn.: Convolvamine)
Product Code L6086
CONVOLAMINE

C17H23NO4
Molecular Formula C17H23NO4
Description

an anesthetic acting on the nerve endings‚ with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator.

Tropane alkaloid C17H23NO4 ‚ from plants of the Convolvulaceae family.
 
Biological Activity

Convolamine presents an anesthetic acting on the nerve endings with a lower activity level than that of Convolvine.
a 2 % solution lowers the sensitive nerve fibers conductivity with a much higher and longer activity as compared with the effect on motor nerve fibers. As with Convolvine‚ Convolamine (1/1000 to 1/3000) inhibits cardiac activity‚ dilates the vessels from isolated ear of rabbit; at 3 mg/kg‚ lowers the arterial pressure in decerebrated cats.
 
Chemical and Physical Properties
 
CAS No. 500-56-1 Molecular Weight 305 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 114-115 °C.
PubChem SID Solubility acetone‚ ethanol‚ DMSO.
Purity 97 % (TLC‚ mass spectrometry). Optical Activity
Toxicity (LD50) mice (s.c.):25-30 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place.Solution for use: 0.1 - 2 %.
Safety Recommendations
 
Bibliographic References
  1. Oreckov et al., Ber (1934). 67:52
 
Prices
Code
Quantity
US $
€uro
L6086
20 mg
56.00
40.00
100 mg
224.00
160.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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