CONVOLVINE - LATOXAN Technical Data Sheet
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L6087 CONVOLVINE

an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator.

Tropane alkaloid C16H21NO4 from plants of the Convolvulaceae family.


PRICES
QuantityUS DollarsEURO
20 mg 61.60 44.00
100 mg 246.40 176.00


  • Molecular Weight : 291 Da.

  • Melting Point : 114-115 °C.

  • Solubility in : acetone, ethanol, methanol.

  • Purity min. : 97 % (TLC, mass spectrometry)

  • Biological Activity : A 0.125 % solution blocks the sensitive nerve endings in frog skin and extends the latency of the reflex response to a painful stimulus. The effect, developing gradually, reaches a maximum 55-60 minutes after application and lasts up to 2 hours. Convolvine (1/1000 to 1/3000) inhibits cardiac activity, dilates the vessels from isolated ear of rabbit; at 3 mg/kg, lowers the arterial pressure in decerebrated cats.

  • Toxicity (LD50) : mice (s.c.): 15-20 mg/kg.

  • Storage recommendations : Store at +4°C, in dark place. Solution for use : 0.1 - 1 %.

  • CAS Reg. No. : 537-30-4

  • Bibliography :
    1. Oreckov et al. Khim. Pharm. Industr. (1933) (Russian). 1:52
    2. Oreckov et al. Journ. Org. Chem. (1937) (Russian). 7:646



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    Revised : 26/04/2007 10:27 - Copyright © Latoxan