non-selective peripheral and central cholinolytic action at the Muscarinic receptors; sedative; antiemetic.

Tropane alkaloid C₁₇H₂₁NO₄.HClO₄ derivative of (-)-Scopolamine from plants of the Datura genus, Solanaceae.

• Molecular Weight : 403.82 Da.
  
  
• Melting Point : 208-209°C.
  
  
• Solubility in : well in water, methanol, ethanol and dimethylformamide.
  
  
• Purity min. : 97 % (TLC, mass spectrometry).
  
  
• Biological Activity : activity close to that of Atropine.
  
  
• Toxicity (LD₅₀) : mice (s.c.; 5% solution): 700-1 300 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place.
  
  
• Merck Index 11th Ed. : 8361
  
  
• Bibliography :
  
  1. Clissold et al., Drugs (1985). 29:190-207