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ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS

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| | L6094 POLYPRENOLS
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presenting an ionophoretic activity by peroxidation of membrane lipids, leading to activation of calcium current through the membrane.
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Polyisoprenoid C55H90O(~3/4), C60H98O(~1/4), C65H106 from plants of the Gossypium genus, Malvaceae.
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| PRICES |
| Quantity | US Dollars | EURO |
10 mg | 100.80 | 72.00 |
5 x 10 mg | 403.20 | 288.00 |
- Molecular Weight : 766 Da.(undecaprenol); 834 Da.(dodecaprenol).
- Solubility in : well in ethanol, chloroform, hexane and acetone.
- Purity min. : 92 %.
- Biological Activity : 5 x 10-5 M multiply by 9 the lipids peroxydation. The ionophoretic activity of Polyprenols is due to this peroxidation of membane lipids and the channels induced in lipid bilayers present a low conductance and a selectivity Ca2+/K+ of 2.5/1.
- Toxicity (LD50) : not toxic.
- Storage recommendations : Stable in dry state during 6-12 months; store at +4°C, in dark place.
- CAS Reg. No. : 308068-00-0
- Bibliography :
- Stone et al., "The characterization of Ficaprenols 10, 11 and 12 from the leaves of Ficus elastica." Biochem. J.(1967) 102(1)325-330
- Wellburn et al., "The characterization and properties of Castapronol 11, 12 and 13 from the leaves of Aesculus hippocastanum." Biochem J. (1967). 102:312-324
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