SONGORINE - LATOXAN Technical Data Sheet
Back to Home Page


ION CHANNEL and RECEPTOR LIGANDS
TOXINS & ALKALOIDS

 
Google Custom Search


L6097 SONGORINE

Adrenergic and Serotonergic stimulant; CNS stimulant; antiarrhythmic.

C20-diterpenoid alkaloid C22H31NO3 from plants of the Aconitum genus, Ranunculaceae.


PRICES
QuantityUS DollarsEURO
5 mg 140.00 100.00
25 mg 560.00 400.00


  • Molecular Weight : 357 Da.

  • Melting Point : 201-203° C.

  • Solubility in : well in chloroform.

  • Purity min. : 98 % (TLC, mass spectrometry, NMR).

  • Biological Activity : antiarrhythmic and CNS stimulant; 25 times as potent as Quinidine and 2 times less toxic; the stimulant effect on the CNS is due to adrenergic and serotonergic stimulation in the reticular formation; causes desynchronization of cortex and sub-cortex action potential rhythms; enhances and prolongs the "reaction of activation" after visual and phonic stimulation; suppresses the electroencephalogram modifications due to intravenous injection of 2 mg/kg Chlorpromazine.

  • Toxicity (LD50) : mice (i.v.): 142.5 mg/kg; mice (i.p.): 485 mg/kg; mice (s.c.): 630 mg/kg; mice (orally): 1 575 mg/kg.

  • Storage recommendations : Store at +4°C, in dark place; solution for use: 10-8 M.

  • CAS Reg. No. : 509-24-0

  • Merck Index 11th Ed. : 8673

  • Bibliography :
    1. De la Fuente et al., Heterocycles (1988). 27:1109



    Latoxan - 20, Rue Léon Blum - F-26000 VALENCE - France
    Phone: +33.4.75.41.91.91 - Fax: +33.4.75.41.91.99
    contact@latoxan.com

    For Research Purposes Only - Not for Human Use.


    Revised : 26/04/2007 10:28 - Copyright © Latoxan