a D₁/D₂ Dopaminergic receptors antagonist in the CNS; Alpha₁ Adrenoreceptors antagonist; possesses a sedative and tranquillizing activity; antiemetic.

Diisoquinoline alkaloid C₁₉H₂₁NO₄.HCl derivative of Scoulerin from plants of the Fumariaceae family.

• Molecular Weight : 363.5 Da.
  
  
• Melting Point : 255-258 C.
  
  
• Solubility in : water; not well in organic solvants.
  
  
• Purity min. : 95 % (TLC).
  
  
• Toxicity (LD₅₀) : mice (i.v.): 275 mg/kg (125-335). rats (s.c.): 168 mg/kg (146-193).
  
  
• Storage recommendations : Store at +4°C, in dark place; recommended concentration in aqueous solution: 0.1%.
  
  
• CAS Reg. No. : 20180-95-4
  
  
• Bibliography :
  
  1. Boit, Ergebnisse der Alkaloid-Chemie bis 1960. Akademie-Verlag, Berlin (1960). p. 420
  2. Brochmann-Hanssen et al., Tetrahed. Letters (1966). 20:2261