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Home Page > Alphabetical Index > METHYLISOCORYDINE IODOMETHYLATE (O-)

METHYLISOCORYDINE IODOMETHYLATE (O-) Prod. No L6204 - CAS # 5489-15-6
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Product Name METHYLISOCORYDINE IODOMETHYLATE (O-)
Product Code L6204
METHYLISOCORYDINE IODOMETHYLATE (O-)

C22H28N+O4I-
Molecular Formula C22H28N+O4I-
Description

a long-lasting ganglioblocker‚ with a sympathetic/parasympathetic activity ratio of 6/1.

Aporphin alkaloid C22H28N+O4I- derivative of Isocorydine from plants of the Corydalis genus‚ Fumariaceae.
 
Biological Activity

hypotensive.
 
Chemical and Physical Properties
 
CAS No. 5489-15-6 Molecular Weight 497.7 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 240-244 °C. (decomp.)
PubChem SID Solubility water (heat up); not well in organic solvants.
Purity 95 % (TLC). Optical Activity
Toxicity (LD50) mice (i.v.): 2.1 mg/kg (1.2-3.6).
mice (s.c.): 8.0 mg/kg (6.1-10.4).
cats (i.v.): 5.0 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place; solution for use: 10-6 to 10-4 g/ml.
Safety Recommendations
 
Bibliographic References
  1. Ribar et al., "Structure of Isocorydine." Acta Crystallographica, section C, (1992). 48(5):945-947
  2. Zhao Yong Qiang et al., "Effects of isocorydine on action potentials in isolated canine Purkinje fibers and ventricular muscles." Zhongguo Yeoli Xuebao (1991). 12(4):324-327
 
Prices
Code
Quantity
US $
€uro
L6204
5 mg
96.60
69.00
25 mg
386.40
276.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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