a long-lasting ganglioblocker, with a sympathetic/parasympathetic activity ratio of 6/1.

Aporphin alkaloid C₂₂H₂₈N⁺O₄I^- derivative of Isocorydine from plants of the Corydalis genus, Fumariaceae.

• Molecular Weight : 497.7 Da.
  
  
• Melting Point : 240-244 °C. (decomp.)
  
  
• Solubility in : water (heat up); not well in organic solvants.
  
  
• Purity min. : 95 % (TLC).
  
  
• Biological Activity : hypotensive.
  
  
• Toxicity (LD₅₀) : mice (i.v.): 2.1 mg/kg (1.2-3.6). mice (s.c.): 8.0 mg/kg (6.1-10.4). cats (i.v.): 5.0 mg/kg.
  
  
• Storage recommendations : Store at +4°C, in dark place; solution for use: 10-6 to 10-4 g/ml.
  
  
• CAS Reg. No. : 5489-15-6
  
  
• Bibliography :
  
  1. Ribar et al., "Structure of Isocorydine." Acta Crystallographica, section C, (1992). 48(5):945-947
  2. Zhao Yong Qiang et al., "Effects of isocorydine on action potentials in isolated canine Purkinje fibers and ventricular muscles." Zhongguo Yeoli Xuebao (1991). 12(4):324-327