a potent anthelmintic: blocks the enzymatic process responsible for the absorption of glucose by parasites, causing their death.

Benzimidazole derivative C₁₂H₁₅N₃O₂S, synthetic.

• Molecular Weight : 265.33 Da.
  
  
• Melting Point : 193-198°C.
  
  
• Solubility in : well in acetic acid; moderately in chloroform; not in 95% ethanol and water.
  
  
• Purity min. : 98%. (IR, UV, TLC [chloroform:diethylic acid:100% cetic acid (6:1:1)]).
  
  
• Physical Form : white crystal powder, sometimes grey-shaded.
  
  
• Chemical Name : 2-methoxycarbonylamino-5-propylthio-1H-benzimidazole.
  
  
• Biological Activity : broad spectrum and potent anthelmintic acting on ascaridosis, tricophacelesis, stronchiloidosis, trichonosis, echinoccocus.
  
  
• Toxicity (LD₅₀) : rat (orally): 500 mg/kg (400-630).
  
  
• Storage recommendations : stable in dry state, store at +4°C, in dark place. Dose for experiment in vivo: 150 mg/kg per day during 3 days or 300 mg/kg in one day.
  
  
• CAS Reg. No. : 54965-21-8
  
  
• Merck Index 11th Ed. : 201
  
  
• Bibliography :
  
  1. Tsizin et al., Khim. Pharm. J. (1986) (Russian). 10:1171