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Home Page > Alphabetical Index > METHIAZOLE

METHIAZOLE Prod. No L6214 - CAS # 74239-55-7
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Product Name METHIAZOLE
Product Code L6214
METHIAZOLE

C12H15N3O2S
Molecular Formula C12H15N3O2S
Description

Broad spectrum anthelmintic; blocks the enzymatic process responsible for the absorption of glucose by parasites‚ causing their death.

Benzimidazole derivative C12H15N3O2S synthetised from 2-methoxy carbonyl aminobenzimidazole
 
Biological Activity

Broad spectrum anthelmintic‚ which efficiency is equal to that of Albendazole. Efficient in cases of polyinvasion‚ especially against echinococcus.
 
Chemical and Physical Properties
 
CAS No. 74239-55-7 Molecular Weight 265.33 Da.
RTECS Physical Form white crystal powder‚ sometimes grey-shaded.
Merck Index No (13th Ed.) Melting point 195-198 °C
PubChem SID Solubility well in acetic acid; moderately in chloroform; practically not in 95% ethanol and water.
Purity 98% TLC [silufol; ether-chloroform-acetic acid (1:6:1)]. Optical Activity
Toxicity (LD50) rat (orally): 500 mg/kg (400-630)
Chemical Names 2-methoxycarbonylamino-5-isopropylthio-1H-benzimidazole
Storage & Reconstitution Recommendations Stable in dry state; store at 4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. The anthelmintic activity of Methiazole was compared to Albendazole's by MN Lebedeva from the Institute of Medical Parasitology and Tropical Medicine in Moscow in Russia.
 
Prices
Code
Quantity
US $
€uro
L6214
100 mg
71.40
51.00
500 mg
285.60
204.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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