Causes cramps; increases arterial blood pressure and breathing frequency.

Tropane alkaloid C₁₆H₂₁NO₄ from plants of the Convolvulus genus, Convolvulaceae.

• Molecular Weight : 291 Da.
  
  
• Melting Point : 209-210 °C.
  
  
• Solubility in : well in ethanol and methanol.
  
  
• Purity min. : 97%. TLC [benzene-methanol (9:1), silicagel, Rf=0.6]
  
  
• Physical Form : cream white powder.
  
  
• Biological Activity : Fillalbin induces clonico-tonic cramps in vivo. The death of mice occurs after 2 or 3 brief cramps.
  In cats, 0.5-3 mg/kg increase arterial blood pressure to about 10-24 mm Hg during 15-60 min. 3 mg/kg increase breathing amplitude and frequency.
  In rabbits, drops of a 1% solution cause an irritation of conjunctiva.
  
  
• Toxicity (LD₅₀) : mice (i.v.): 15 mg/kg.
  mice (s.c.): 25 mg/kg.
  
  
• Storage recommendations : Stable when kept dry, store at +4°C, in dark and dry place. Solution for use: 0.1-1 %.
  
  
• CAS Reg. No. : 4540-25-4
  
  
• Bibliography :
  
  1. Sharapova et al., Chem. Nat. Comp. (1980). 5