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Home Page > Alphabetical Index > FILLALBIN

FILLALBIN Prod. No L6225 - CAS # 4540-25-4
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Product Name FILLALBIN
Product Code L6225
FILLALBIN

C16H21NO4
Molecular Formula C16H21NO4
Description

Causes cramps; increases arterial blood pressure and breathing frequency.

Tropane alkaloid C16H21NO4 ‚ from plants of the Convolvulus genus‚ Convolvulaceae.
 
Biological Activity

Fillalbin induces clonico-tonic cramps in vivo. The death of mice occurs after 2 or 3 brief cramps.

In cats‚ 0.5-3 mg/kg increase arterial blood pressure to about 10-24 mm Hg during 15-60 min. 3 mg/kg increase breathing amplitude and frequency.


In rabbits‚ drops of a 1% solution cause an irritation of conjunctiva.
 
Chemical and Physical Properties
 
CAS No. 4540-25-4 Molecular Weight 291 Da.
RTECS Physical Form cream white powder.
Merck Index No (13th Ed.) Melting point 209-210 °C.
PubChem SID Solubility well in ethanol and methanol.
Purity 97%. TLC [benzene-methanol (9:1)‚ silicagel‚ Rf=0.6] Optical Activity [a]D +- 0°.
Toxicity (LD50) mice (i.v.): 15 mg/kg.

mice (s.c.): 25 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Stable when kept dry‚ store at +4°C‚ in dark and dry place. Solution for use: 0.1-1 %.
Safety Recommendations
 
Bibliographic References
  1. Sharapova et al., Chem. Nat. Comp. (1980). 5
 
Prices
Code
Quantity
US $
€uro
L6225
10 mg
71.40
51.00
50 mg
285.60
204.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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