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Home Page > Alphabetical Index > AMMODYTOXIN

AMMODYTOXIN Prod. No L8105 - CAS # 97089-72-0
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Product Name AMMODYTOXIN
Product Code L8105
AMMODYTOXIN
Molecular Formula
Description

a toxic presynaptic Phospholipase A2 also referred to as toxin "k2".

122- amino acid protein with 7 disulfide bridges ‚ from Vipera ammodytes snake venom.
 
Biological Activity

mode of action (4): blocks neuromuscular transmission by acting selectively at the presynaptic site.
 
Chemical and Physical Properties
 
CAS No. 97089-72-0 Molecular Weight 13‚775 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point
PubChem SID Solubility well in water and saline.
Purification: gel filtration on Sephadex G-100 and ion exchange chromotography on CM-cellulose.
Purity Optical Activity
Toxicity (LD50) mice (i.v.): 0.021 mg/kg (3).
Chemical Names
Storage & Reconstitution Recommendations stable in freeze-dried state. In solution‚ keep at -20°C.
Safety Recommendations
 
Bibliographic References
  1. Gubensek et al., Period. Biol. (1980). 82:444-447
  2. Ritonja et al., Biochimica et Biophysica Acta (1985). 828:306-312
  3. Thouin et al., Toxicon, (1982) 20:1051-1058
  4. Lee, C.Y., Tsai, M.C., Chen, Y.M., Ritonja, A. & Gubensek, F., Arch. Int. Pharmacodyn., 268, 313-324.
 
Prices
Code
Quantity
US $
€uro
L8105-250UG
1 x 250 µg
95.20
68.00
5 x 250 µg
380.80
272.00
L8105-1MG
1 x 1 mg
357.00
255.00
5 x 1 mg
1 428.00
1 020.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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