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Venoms - Toxins - Alkaloids - Plant Compounds - Ion Channel & Receptor Ligands

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Home Page > Alphabetical Index > SCYLLATOXIN ([Tyr ²]-)

SCYLLATOXIN ([Tyr ²]-) Prod. No L8206 - CAS #
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Product Name SCYLLATOXIN ([Tyr ²]-)
(Syn.: [Tyr2]-Leiurotoxin I)
Product Code L8206
SCYLLATOXIN ([Tyr ²]-)
Molecular Formula
Description

a blocker of Apamin-sensitive Ca2+-activated K+ channels‚ like Scyllatoxin; [Tyr2]-Scyllatoxin allows labelling by iodination.

31-amino acid polypeptide with 3 disulfide bridges. ‚ synthetic‚ originally from Leiurus quinquestriatus hebraeus scorpion venom.
 
Biological Activity

 
Chemical and Physical Properties
 
CAS No. Molecular Weight 3‚447 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point
PubChem SID Solubility well in water and saline.
Purity 95 %. Optical Activity
Toxicity (LD50)
Chemical Names
Storage & Reconstitution Recommendations Stable in freeze-dried state. In solution‚ keep at - 20 °C.
Safety Recommendations
 
Bibliographic References
  1. Chicci et al., "Purification and characterization of a unique, potent inhibitor of apamin binding from Leiurus quinquestriatus hebraeus venom." J. Biol. Chem.,(1988). 263(21):10192-10197
  2. Auguste et al., "Leiurotoxin I (Scyllatoxin), a peptide ligand for Ca2+-activated K+ channels." J. Biol. Chem., (1990) 265(8):4753-4759
  3. Martins et al., FEBS Letters,(1990) 260(2):249-253
 
Prices
Code
Quantity
US $
€uro
L8206
1 x 50 µg
280.00
200.00
5 x 50 µg
1 120.00
800.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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