a blocker of small-conductance Cl- channels derived from epithelial cells when applied to the cytoplasmic surface.

36-amino acid peptide with 4 disulfide bridges, from Leiurus quinquestriatus scorpion venom.

• Molecular Weight : 3,997 Da.
  
  
• Solubility in : well in water and saline.
  
  
• Purity min. : 95.5 % (HPLC).
  
  
• Storage recommendations : stable in freeze-dried state. In solution, keep at -20°C.
  
  
• CAS Reg. No. : 163515-35-3
  
  
• Bibliography :
  
  1. DeBin et al., "Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion." Am. J. Physiol. 264 (Cell Physiol. 33) (1993). C361-C369
  2. Lippens et al., "NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels." Biochemistry (1995). 34:13-21
  3. J. Najib, P. Sautičre, J.C. Gesquičre and A. Tartar, "Innovation and Perspective in Solid Phase Synthesis", R. Epton, Mayflower Worldwide, Birmingham (1994) 615