Print
this page
LATOXAN
20
Rue Léon Blum
26000
Valence - France
Fax : (+33) 47 541 9199
Email : contact@latoxan.com
Contact Us
|
LATOXAN |
| Venoms - Toxins - Alkaloids
- Plant Compounds - Ion Channel & Receptor Ligands
|
Phone : (+33) 47 541 9191 Fax : (+33) 47 541 9199 Email : contact@latoxan.com Contact Us |
Home Page > Alphabetical Index > Lqh Alpha IT
| Lqh Alpha IT Prod. No L8221 - CAS # |
| Product Name | Lqh Alpha IT |
|
| Product Code | L8221 |  |
| Molecular Formula | ||
| Description | an α-scorpion insect toxin‚ which prolongs the evoked action potential by an inhibition of sodium inactivation in insects and mammals. 64-amino acid polypeptide with 4 disulfide bridges‚ ‚ from Leiurus quinquestriatus hebraeus venom. |
|
| Biological Activity | Lqh aIT is highly toxic to insects; it also presents a toxicity to crustaceans and has a low‚ but measurable toxicity to mice. Lqh aIT causes an extreme prolongation of the action potential in both cockroach giant axon and rat skeletal muscle preparations as a result of the slowing and incomplete inactivation of the sodium currents (1). |
||||||||||||||
| Chemical and Physical Properties | |||||||||||||||
| CAS No. | Molecular Weight | 7‚231.4 Da. | |||||||||||||
| RTECS | Physical Form | ||||||||||||||
| Merck Index No (13th Ed.) | Melting point | ||||||||||||||
| PubChem SID | Solubility | well in water and saline. | |||||||||||||
| Purity | 96 % (capillary electrophoresis). | Optical Activity | |||||||||||||
| Toxicity (LD50) | blowfly larvae: delayed sustained contraction paralysis (PU50): 140 ng/g; isopods (terrestrial crustaceans): paralysis within 5 mn (PU50): 200 ng/g; mice: lethality observed after 24 h (LD50): 5 µg/kg. |
||||||||||||||
| Chemical Names | |||||||||||||||
| Storage & Reconstitution Recommendations | store at 4°C. | ||||||||||||||
| Safety Recommendations | |||||||||||||||
| Bibliographic References |
|
||||||||||||||
| Prices |
|
||||||||||||||
| External Links |  PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID |
||||||||||||||
[ Ordering Information ] - [ Privacy Statement ] - [ Infos Légales ] - [ Contact Us ] © Copyright of Latoxan SAS 2008 - France. For Research Pharmaceutical and Medical Purposes Only. DOCUMENT URL : http://www.latoxan.com/PHP/00000144.php |
|||||||||||||||
| ModelBtx.html - Last Update 14/08/2009 11:47:11 | |||||||||||||||