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Home Page > Alphabetical Index > PLAČ

PLAČ Prod. No L8408 - CAS # 9001-84-7
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Product Name PLAČ
Product Code L8408
PLAČ
Molecular Formula
Description

the main antigen of bee venom‚ causing hydrolysis of erythrocytes and mast cells membrane phospholipids‚ and acting in synergy with Melittin.

Protein‚ ‚ from Apis mellifera bee venom.
 
Biological Activity

activity > 850 units per mg protein at pH 8.9 at 25 °C.‚ using egg yolk phosphatidylcholine.
 
Chemical and Physical Properties
 
CAS No. 9001-84-7 Molecular Weight ~ 18‚500 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point
PubChem SID Solubility soluble in water.
Purity 96 %. (HPLC‚ amino acid analysis) Optical Activity
Toxicity (LD50) mice (i.p.): 0.37 ”g/g.
Chemical Names
Storage & Reconstitution Recommendations stable in dried state; store at 4°C.
Safety Recommendations
 
Bibliographic References
  1. Hollander et al., "Characterization of the oligosaccharide structures on bee venom phospholipase A2." Carbohydrate Research (1993). 247:291-297
  2. Kubelka et al., "Primary structures of the N-linked carbohydrate chains from honeybee venom phospolipase A2." European Journal of Biochemistry (1993). 213(3):1193-1204
  3. Prenner et al., "The antigenicity of the carbohydrate moiety of an insect glycoprotein, honey-bee (Apis mellifera) venom phospholipase A2: the role of alpha 1,3-fucosylation of the asparagine-bound N-acetylglucosamine." Biochemical Jl (London 1984) (1992)
  4. Slotta et al., "Enzymatic and toxic activity of phospholipase A." in A. De Vries and E. Kochva, Eds., Toxins of Animal and Plant Origin, Vol. I, Gordon and Breach, New-York (1971), 401-418.
 
Prices
Code
Quantity
US $
€uro
L8408
1 x 1 mg
71.40
51.00
5 x 1 mg
285.60
204.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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