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Home Page > Alphabetical Index > BREVETOXIN PbTx-3

BREVETOXIN PbTx-3 Prod. No L8902 - CAS # 85079-48-7
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Product Name BREVETOXIN PbTx-3
Product Code L8902
BREVETOXIN PbTx-3

C50H72O14

Molecular Formula C50H72O14
Description

an activator of voltage-sensitive Na+ channels.

C50H72O14 ‚ from the microorganism Ptychodiscus brevis.

 
Biological Activity

 
Chemical and Physical Properties
 
CAS No. 85079-48-7 Molecular Weight 897.11 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 291-293 °C. (decomp.)
PubChem SID 24822038 Solubility acetone‚ ethyl acetate‚ methanol‚ ethanol‚ water.
Purity 95 % (HPLC). Optical Activity
Toxicity (LD50)
Chemical Names
Storage & Reconstitution Recommendations Brevetoxins are unusually stable materials in the dry state under vacuum. It is recommended that PbTx–3 be stored at -20°C in its original unopened vial until use. Once opened‚ PbTx–3 should be dissolved in an appropriate solvent like acetone‚ acetonitrile‚ alcohol or ethyl acetate for preparation of stock solutions. Use of Dymethyl sufoxide (DMSO) is specifically discouraged because of its ability to carry toxic materials across membranes.

PbTx–3 is stable in solvents‚ including water‚ where half-lives for active material range from 4-6 months. Stock solutions may be stored in a dry argon or nitrogen atmosphere in solution‚ or aliquots may be prepared from the stock solution and dispensed into individual vials for resealing under vacuum if desired. Unopened vials of Brevetoxin PbTx–3 are stable at freezer temperatures for a minimum of 6 months.

Packaging:crystalline solid in sealed ampoule under vacuum.
Safety Recommendations
 
Bibliographic References
  1. Shimizu et al., J. Am. Chem. Soc.(1986) 108:514
  2. Trainer et al., ACS, Symposium series(1990) 418:166
 
Prices
Code
Quantity
US $
Euro (¤)
L8902
1 x 100 µg
518,00
370,00
5 x 100 µg
2 072,00
1 480,00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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