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ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS

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| | L9001 CLOFLUBICYNE
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| PRICES |
| Quantity | US Dollars | EURO |
1 mg | 154.00 | 110.00 |
5 x 1 mg | 616.00 | 440.00 |
- Molecular Weight : 351 Da.
- Melting Point : 122-126 °C.
- Solubility in : soluble in alcohol, alcohol + water and acetone.
- Purity min. : 95 % (NMR).
- Biological Activity : (IC50) for blocking the GABA-dependent [36Cl] uptake in rat brain synaptosomes:10 nM.
inhibition of the GABA-dependent Cl- current: 5.3 nM;
experiments with [3H]-labelled GABA-competitive ligands (Muscimol, Flunitrazepam) showed no influence of Cloflubicyne up to 10 µM.
- Toxicity (LD50) : mice (i.p.): 0.1 mg/kg.
rat (orally): 0.2 mg/kg.
- Storage recommendations : store at room temperature.
1 mg Cloflubicyne can be dissolved in 1 ml ethanol (up to 50 °C), then diluted in distilled water. Solution for experiments must contain less than 0.5 % ethanol and be stored at 0 °C.
- CAS Reg. No. : 224790-70-9
- Bibliography :
- Middelton et al., J. Fluor. Chem.(1982) 20:397-418
- Fetisov et al., J. Fluor. Chem.(1991) 54:301
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Revised : 26/04/2007 10:27 - Copyright © Latoxan |
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