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ION CHANNEL and RECEPTOR LIGANDS TOXINS & ALKALOIDS

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| | L9002 FLUCYBENE
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| PRICES |
| Quantity | US Dollars | EURO |
1 mg | 81.20 | 58.00 |
5 x 1 mg | 324.80 | 232.00 |
- Molecular Weight : 280 Da.
- Melting Point : 182-183 °C.
- Solubility in : well in alcohol, alcohol + water and acetone.
- Purity min. : 95 % (NMR).
- Biological Activity : (IC50) for blocking the GABA-dependent [36Cl] uptake in rat brain synaptosomes: 50 nM;
inhibition of the GABA-dependent Cl- current at 61.0 nM;
experiments with [3H]-labelled GABA-competitive ligands (muscimol, GABA) showed no influence of Flucybene up to 10 µM.
- Toxicity (LD50) : mice (i.p.): 1.0 mg/kg.
rat (orally): 1.5 mg/kg.
- Storage recommendations : store at room temperature. 1 mg Cloflubicyne can be dissolved in 1 ml ethanol (up to 50 °C), then diluted in distilled water. Solution for experiments must contain less than 0.5 % ethanol and be stored at 0 °C.
- CAS Reg. No. : 3289-22-3
- Bibliography :
- Middelton et al., J. Fluor. Chem.(1982) 20:397-418
- Fetisov et al., J. Fluor. Chem.(1991) 54:301
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Revised : 26/04/2007 10:27 - Copyright © Latoxan |
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