an irreversible inhibitor of serine proteinase a-thrombine, more active than Diisopropylfluorophosphate.

C₁₉H₁₂F₁₂NO₂P, synthetic.

• Molecular Weight : 545.27 Da.
  
  
• Melting Point : 172-173 °C.
  
  
• Solubility in : well in chloroform, acetone and DMSO.
  
  
• Purity min. : 99 % (NMR).
  
  
• Biological Activity : irreversible serine proteinase a-thrombine inhibition constants:
  Ki = 7 x 10-5 M;
  ki = 1.1 x 104 M-1.min-1;
  k2 = 0.8 min-1.
  
  
• Toxicity (LD₅₀) : mice (orally): 3 120 mg/kg.
  
  
• Storage recommendations : store at room temperature.
  
  
• CAS Reg. No. : 142450-99-5
  
  
• Bibliography :
  
  1. Kireeva et al., Biochemistry (1992) (Russian). 57(1):21