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ETBICYTHIONAT Prod. No L9015 - CAS # 224790-71-0
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Product Name ETBICYTHIONAT
Product Code L9015
ETBICYTHIONAT

C6H11O3PS
Molecular Formula C6H11O3PS
Description

a potent non-competitive GABA antagonist in mammals; causes epileptoform seizures.

Organophosphorous compound‚ C6H11O3PS ‚ synthetic.
 
Biological Activity

IC50 for GABA-dependent [36Cl] uptake blockade in rat brain synaptosomes: 0.2 nM;

IC50 for [35S]-tert.butyl-thionebicyclophosphate binding (Housefly brain membranes):
3.2 µM.
 
Chemical and Physical Properties
 
CAS No. 224790-71-0 Molecular Weight 194.19 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 179 °C.
PubChem SID Solubility soluble in ethanol and ethanol + water.
Purity 98 % (NMR). Optical Activity
Toxicity (LD50) mice (i.p.): 1.1 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at room temperature; solution for use: 1 mg/ml in ethanol (dilution is then possible in an equal volume of water).
Safety Recommendations
 
Bibliographic References
  1. Wadswort et al., J. Am. Chem. Soc. (1962) 84(2):610
  2. Squires et al., Mol. Pharmacol.(1983) 23:326-331
  3. Cohen et al., Pest. Biochem. Physiol.(1986) 25(1):63
 
Prices
Code
Quantity
US $
€uro
L9015
1 x 100 µg
159.60
114.00
5 x 100 µg
638.40
456.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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