TETS - LATOXAN Technical Data Sheet
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ION CHANNEL and RECEPTOR LIGANDS
TOXINS & ALKALOIDS

 
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L9016 TETS
( Tetramethylenedisulfotetramide )

GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.

  1. see annexed table : Compared Activities of some Cl- Channel Blockers....

Sulfur-nitrogen heterocycle heteroadamantane, C4H8N4O4S2, synthetic.


PRICES
QuantityUS DollarsEURO
50 µg 117.60 84.00
5 x 50 µg 470.40 336.00


  • Molecular Weight : 240.26 Da (NMR).

  • Melting Point : > 270 °C.

  • Solubility in : water and DMSO; moderately in acetone; insoluble in methanol and ethanol.

  • Purity min. : 97 %.

  • Biological Activity : IC50 for GABAA-dependent [36Cl]-uptake blockade: 0.5 µM (mouse brain).

  • Toxicity (LD50) : mice (i.p.): 0.24 mg/kg.

  • Storage recommendations : store at room temperature.

  • CAS Reg. No. : 199488-98-7

  • Merck Index 11th Ed. : 9158

  • Bibliography :
    1. Esser et al. Chem. Res. Toxicol.(1991) 4(2):162
    2. Casida et al., Toxicol. Appl. Pharmacol. (1976). 36:261



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    Revised : 26/04/2007 10:28 - Copyright © Latoxan