LK-66 Prod. No L9022 - Latoxan - Valence

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LK-66 Prod. No L9022 - CAS # 36944-86-2

Product Name	LK-66
Product Code	L9022	C₁₆H₂₀NS₂I
Molecular Formula	C₁₆H₂₀NS₂I
Description	a highly selective M₁ Muscarinic receptor antagonist. Quaternary ammonium salt‚ C₁₆H₂₀NS₂I ‚ synthetic.

Biological Activity

pIC₅₀ (= -log IC₅₀):M₁ (rat brain) = 8.46

M₂ (heart) = 5.10

selectivity: [IC₅₀]M₂ / [IC₅₀]M₁= 2291

data determined by [³H]-QNB binding method‚ Pirenzepine as standard (unpublished).

Chemical and Physical Properties

CAS No.

36944-86-2

Molecular Weight

417.37 Da.

RTECS

Physical Form

Merck Index No (13th Ed.)

Melting point

216-218 °C.

PubChem SID

Solubility

water (heat up)‚ ethanol.

Purity

95 % (NMR).

Optical Activity

Toxicity (LD50)

Chemical Names

Storage & Reconstitution Recommendations

Store at +4°C‚ in dark place. Solution for use: 10-3 M.

Safety Recommendations

Bibliographic References

V. Malyguin et al.; XIII int. symp. Med. Chem. (Paris : 19-24 sept.); Abstr.; 312 (1994).

Prices

Code

Quantity

US $

uro

L9022

1 x 2 mg

96.60

69.00

5 x 2 mg

386.40

276.00

External Links

PubMed

Biomedical Citations From PubMed

Toxicology Citations From PubMed

PubChem SID

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