LK-66 - LATOXAN Technical Data Sheet
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ION CHANNEL and RECEPTOR LIGANDS
TOXINS & ALKALOIDS

 
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L9022 LK-66

a highly selective M1 Muscarinic receptor antagonist.

Quaternary ammonium salt, C16H20NS2I, synthetic.


PRICES
QuantityUS DollarsEURO
2 mg 96.60 69.00
5 x 2 mg 386.40 276.00


  • Molecular Weight : 417.37 Da.

  • Melting Point : 216-218 °C.

  • Solubility in : water (heat up), ethanol.

  • Purity min. : 95 % (NMR).

  • Biological Activity : pIC50 (= -log IC50):M1 (rat brain) = 8.46
    M2 (heart) = 5.10
    selectivity: [IC50]M2 / [IC50]M1= 2291
    data determined by [3H]-QNB binding method, Pirenzepine as standard (unpublished).

  • Storage recommendations : Store at +4°C, in dark place. Solution for use: 10-3 M.

  • CAS Reg. No. : 36944-86-2

  • Bibliography :
    1. V. Malyguin et al.; XIII int. symp. Med. Chem. (Paris : 19-24 sept.); Abstr.; 312 (1994).



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    Revised : 26/04/2007 10:27 - Copyright © Latoxan