LK-190 - LATOXAN Technical Data Sheet
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ION CHANNEL and RECEPTOR LIGANDS
TOXINS & ALKALOIDS

 
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L9027 LK-190

a Muscarinic receptors antagonist.

Ammonium salt, quinuclidine derivative, C20H21N.HCl synthetic.


PRICES
QuantityUS DollarsEURO
2 mg 74.20 53.00
5 x 2 mg 296.80 212.00


  • Molecular Weight : 311.85 Da.

  • Melting Point : 261-263°C

  • Solubility in : water + ethanol; water (heat up).

  • Purity min. : min. 98 % (TLC, NMR).

  • Biological Activity : pIC50 (= -log IC50): M1 (rat brain) = 7.12
    M2 (heart) = 6.43
    selectivity:[IC50]M2 / [IC50]M1 = 4.89
    determined by [3H]-QNB binding method, Pirenzepine as standard (unpublished).

  • Toxicity (LD50) : mice (orally): 106 mg/kg.

  • Storage recommendations : Store at +4°C, in dark place. Solution for use: 10-3 M.

  • CAS Reg. No. : 60697-89-4

  • Bibliography :
    1. Michlina et al., Chim. Heterocycl. Soed. (1976) (Russian). 7:935



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    Revised : 26/04/2007 10:27 - Copyright © Latoxan