LK-190 Prod. No L9027 - Latoxan - Valence

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LK-190 Prod. No L9027 - CAS # 60697-89-4

Product Name	LK-190
Product Code	L9027	C₂₀H₂₁N.HCl
Molecular Formula	C₂₀H₂₁N.HCl
Description	a Muscarinic receptors antagonist. Ammonium salt‚ quinuclidine derivative‚ C₂₀H₂₁N.HCl ‚ synthetic.

Biological Activity

pIC₅₀ (= -log IC₅₀): M₁ (rat brain) = 7.12
M₂ (heart) = 6.43

selectivity:[IC₅₀]_M2 / [IC₅₀]_M1 = 4.89

determined by [³H]-QNB binding method‚ Pirenzepine as standard (unpublished).

Chemical and Physical Properties

CAS No.

60697-89-4

Molecular Weight

311.85 Da.

RTECS

Physical Form

Merck Index No (13th Ed.)

Melting point

261-263°C

PubChem SID

Solubility

water + ethanol; water (heat up).

Purity

min. 98 % (TLC‚ NMR).

Optical Activity

Toxicity (LD50)

mice (orally): 106 mg/kg.

Chemical Names

Storage & Reconstitution Recommendations

Store at +4°C‚ in dark place. Solution for use: 10^-3 M.

Safety Recommendations

Bibliographic References

Michlina et al., Chim. Heterocycl. Soed. (1976) (Russian). 7:935

Prices

Code

Quantity

US $

uro

L9027

1 x 2 mg

74.20

53.00

5 x 2 mg

296.80

212.00

External Links

PubMed

Biomedical Citations From PubMed

Toxicology Citations From PubMed

PubChem SID

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