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Home Page > Alphabetical Index > LK-190

LK-190 Prod. No L9027 - CAS # 60697-89-4
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Product Name LK-190
Product Code L9027
LK-190

C20H21N.HCl

Molecular Formula C20H21N.HCl
Description

a Muscarinic receptors antagonist.

Ammonium salt‚ quinuclidine derivative‚ C20H21N.HCl ‚ synthetic.

 
Biological Activity

pIC50 (= -log IC50): M1 (rat brain) = 7.12
M2 (heart) = 6.43

selectivity:[IC50]M2 / [IC50]M1 = 4.89

determined by [3H]-QNB binding method‚ Pirenzepine as standard (unpublished).

 
Chemical and Physical Properties
 
CAS No. 60697-89-4 Molecular Weight 311.85 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 261-263°C
PubChem SID Solubility water + ethanol; water (heat up).
Purity min. 98 % (TLC‚ NMR). Optical Activity
Toxicity (LD50) mice (orally): 106 mg/kg.
Chemical Names
Storage & Reconstitution Recommendations Store at +4°C‚ in dark place. Solution for use: 10-3 M.
Safety Recommendations
 
Bibliographic References
  1. Michlina et al., Chim. Heterocycl. Soed. (1976) (Russian). 7:935
 
Prices
Code
Quantity
US $
€uro
L9027
1 x 2 mg
74.20
53.00
5 x 2 mg
296.80
212.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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