a Muscarinic receptors antagonist.

Ammonium salt, quinuclidine derivative, C₂₀H₂₃NO.HCl, synthetic.

• Molecular Weight : 329.87 Da.
  
  
• Melting Point : 173-175 °C.
  
  
• Solubility in : water.
  
  
• Purity min. : min. 98 %. (TLC, NMR).
  
  
• Biological Activity : pIC₅₀(= -log IC₅₀): M₁ (rat brain) = 7.22 M₂ (heart) = 6.28
  selectivity: [IC₅₀]_M2/[IC₅₀]_M1 = 8.71
  determined by [³H]-QNB binding method, Pirenzepine as standard (unpublished).
  
  
• Storage recommendations : store at +4°C, in dark place.
  
  
• CAS Reg. No. : 23167-49-9
  
  
• Bibliography :
  
  1. Nilsson et al., J. Med. Chem. (1969). 12:1103-1105