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Home Page > Alphabetical Index > LK-252

LK-252 Prod. No L9028 - CAS # 23167-49-9
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Product Name LK-252
Product Code L9028
LK-252

C20H23NO.HCl

Molecular Formula C20H23NO.HCl
Description

a Muscarinic receptors antagonist.

Ammonium salt‚ quinuclidine derivative‚ C20H23NO.HCl ‚ synthetic.

 
Biological Activity

pIC50(= -log IC50): M1 (rat brain) = 7.22 M2 (heart) = 6.28

selectivity: [IC50]M2/[IC50]M1 = 8.71

determined by [3H]-QNB binding method‚ Pirenzepine as standard (unpublished).

 
Chemical and Physical Properties
 
CAS No. 23167-49-9 Molecular Weight 329.87 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 173-175 °C.
PubChem SID Solubility water.
Purity min. 98 %. (TLC‚ NMR). Optical Activity
Toxicity (LD50)
Chemical Names
Storage & Reconstitution Recommendations store at +4°C‚ in dark place.
Safety Recommendations
 
Bibliographic References
  1. Nilsson et al., J. Med. Chem. (1969). 12:1103-1105
 
Prices
Code
Quantity
US $
€uro
L9028
1 x 2 mg
74.20
53.00
5 x 2 mg
296.80
212.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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