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Home Page > Alphabetical Index > NANOPHINE

NANOPHINE Prod. No L9042 - CAS #
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Product Name NANOPHINE
(Syn.: cis-)
Product Code L9042
NANOPHINE

C7H15N .HCl
Molecular Formula C7H15N .HCl
Description

a neuronal nicotinic AChR antagonist. Ganglioblocker. Hypotensive. Good penetration of biological membranes. Cis-dimethylsubstituted analog of Tempidine and Temechine.

Alkaloid‚ C7H15N .HCl ‚ synthetic.
 
Biological Activity

For comparative information see the attached 3 tables.

Central nicotinic acetylcholine receptor blocker without action on skeleton muscle innervation.less potent than PEMPIDINE.

Good penetration of biological membranes.
 
Chemical and Physical Properties
 
CAS No. Molecular Weight 149.66 Da.
RTECS Physical Form colorless crystal powder.
Merck Index No (13th Ed.) Melting point > 250°C
PubChem SID Solubility water‚ ethanol.
Purity min. 99.5%.

TLC [Silufol UV-254‚ MeOH:NH3(25%) Rf = 0.23‚ development with Dragendorff¨ reagent]; NMR (D2O).		 Optical Activity
Toxicity (LD50) min. 99.5%.

TLC [Silufol UV-254 MeOH:NH3(25%) Rf = 0.23 development with Dragendorff¨ reagent]; NMR (D2O).
Chemical Names cis-2‚6-dimethylpiperidine hydrochloride.
Storage & Reconstitution Recommendations store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 13.33 ml)‚ stable for 1-2 days at 20°C.
Safety Recommendations do not swallow or inhale; avoid eye and skin contact.
 
Bibliographic References
 
Prices
Code
Quantity
US $
€uro
L9042
1 x 2 mg
60.20
43.00
5 x 2 mg
240.80
172.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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