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Home Page > Alphabetical Index > TEMPIDONE
| TEMPIDONE Prod. No L9046 - CAS # 826-36-8 |
| Product Name | TEMPIDONE (Syn.: Triacetonamine Vincubine TMP=O) |
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| Product Code | L9046 | ![]() C9H17NO .HCl |
| Molecular Formula | C9H17NO .HCl | |
| Description | a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Sedative. Secondary analog of Pempidone. Antioxidant radical scavenger. Piperidine derivative C9H17NO .HCl synthetic. |
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| Biological Activity | For comparative information see the attached tables. |
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| Chemical and Physical Properties | |||||||||||||||
| CAS No. | 826-36-8 | Molecular Weight | 191.70 Da. | ||||||||||||
| RTECS | Physical Form | colorless crystal powder. | |||||||||||||
| Merck Index No (13th Ed.) | Melting point | 195-196 °C. | |||||||||||||
| PubChem SID | Solubility | water ethanol. | |||||||||||||
| Purity | min. 99.5%. TLC (Silufol UV-254 MeOH:NH3(25%) Rf 0.41 development with Dragendorff¨ reagent); NMR (D2O). |
Optical Activity | |||||||||||||
| Toxicity (LD50) | mice (orally): 200-230 mg/kg - mice (i.v.): 860-950 mg/kg; rats (i.v.): 600-700 mg/kg. - mice (i.p.): 350-400 mg/kg; rats (i.p.): 600-700 mg/kg - mice (i.m.): 500 mg/kg |
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| Chemical Names | 2266-tetramethylpiperidone-4 hydrochloride. | ||||||||||||||
| Storage & Reconstitution Recommendations | store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 10.43 ml) stable for 1-2 days at 20°C. | ||||||||||||||
| Safety Recommendations | |||||||||||||||
| Bibliographic References |
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