an anticoagulant.

Complex of lanthanide element, Nd(C₅O₄NH₈)₃ .7H₂O, synthetic.

• Molecular Weight : 708 Da.
  
  
• Melting Point : ~ 200°C.
  
  
• Solubility in : well in water and ethanol.
  
  
• Purity min. : min. 97%. (chemical elemental analysis, IR)
  
  
• Physical Form : pink powder.
  
  
• Chemical Name : Neodymium tris-hydrogeneglutaminate.
  
  
• Biological Activity : The lanthanide element from Glutaned replaces calcium in its complex with prothrombine, thus preventing the formation of thrombine and interrupting the blood coagulation process.
  On rabbits, i.v., the blood anticoagulating action appears after 0,5-1 hour. In vivo, the maximum effect occurs after 3 hours, the duration of action is 5 hours [1]. In vitro, the action of 0.02 - 0.5 % solutions appears after 30.00 ± 0.08 seconds. Standard: 20.00 ± 0.06 seconds.
  
  
• Storage recommendations : store in dry state or in saline, at room temperature. Solution for use: 2.5% - 5%. Dose for one experiment in vivo: 5 mg.
  
  
• Safety recommendations : Low toxicity.
  
  
• CAS Reg. No. : 148822-97-3
  
  
• Bibliography :
  
  1. Divald et al., "Coagulants and anticoagulants in medicinal chemistry", Burger Ed., 3rd ed., Part II, Wiley Int., N.Y., (1970). 1092-1122
  2. Vestn. Mosc. Univ. Ser 2, Chimia (1992) (Russian). 33(6):565-570