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Home Page > Alphabetical Index > OXYLIDIN HCl

OXYLIDIN HCl Prod. No L9056 - CAS # 7348-26-7
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Product Name OXYLIDIN HCl
(Syn.: Q-Obz)
Product Code L9056
OXYLIDIN HCl

C14H17NO2.HCl
Molecular Formula C14H17NO2.HCl
Description

Weak AChR antagonist. Phenyl analog of ACECLIDINE. Hypotensive. Antiarrhythmic. Sedative (cortex and reticulum). Good penetration of biological membranes.

Quinuclidine derivative‚ C14H17NO2.HCl ‚ synthetic.
 
Biological Activity

No actual mechanism of biological action is known.


weak antagonist of M and N cholinoreceptors. changes the electrical activity of the brain. weak spasmolytic. causes hypotension due to moderate ganglioblocking and adrenolytic activity. sedative; enhances narcotics‚ hypnotics‚ analgesics and local anesthetics action.

good penetration of biological membrane.

does not relax skeletal muscles.
 
Chemical and Physical Properties
 
CAS No. 7348-26-7 Molecular Weight 267.75 Da.
RTECS Physical Form colorless crystal powder.
Merck Index No (13th Ed.) Melting point 246-250 °C.
PubChem SID Solubility water‚ ethanol.
Purity min. 98%. (TLC [MeOH-NH3 25% (10:1)‚ Rf: 0.41‚ Sulifol]). Optical Activity
Toxicity (LD50) rats (orally): 250 mg/kg.
Chemical Names DL-3-benzoyloxyquinuclidine hydrochloride.
Storage & Reconstitution Recommendations Store at room temperature. Solution for use:dissolve in water: 10-3M (2 mg in 7.46 ml)‚ stable for 1-2 days at 20°C.
Safety Recommendations Do not swallow or inhale; avoid eye and skin contact.
 
Bibliographic References
  1. Mashkovsky et al., Prog. Drug. Res. (1969). 13:294-339
  2. Leniva et al., Kardiologiya (1973) (Russian). (4):142-143
  3. Mashkovsky et al., Farm. Toxicol. (1962) (Russian). 25(6):32-37
  4. Ziatzeva et al., Farm. Toxicol. (1970) (Russian). 33(3):305-309
 
Prices
Code
Quantity
US $
€uro
L9056
1 x 2 mg
96.60
69.00
5 x 2 mg
386.40
276.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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