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Home Page > Alphabetical Index > ETHOQUINE

ETHOQUINE Prod. No L9064 - CAS # 112300-33-1
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Product Name ETHOQUINE
(Syn.: Q-COOEt)
Product Code L9064
ETHOQUINE

C10H17NO2.HCl

Molecular Formula C10H17NO2.HCl
Description

AChR agonist. Rigid bicyclic analog of ACh and ARECOLINE. Good penetration of biological membranes.

Quinuclidine derivative‚ C10H17NO2.HCl ‚ synthetic.

 
Biological Activity

Weak muscarinic agonist. Weak nicotinic antagonist.

 
Chemical and Physical Properties
 
CAS No. 112300-33-1 Molecular Weight 219.71 Da.
RTECS Physical Form
Merck Index No (13th Ed.) Melting point 162-163 °C.
PubChem SID Solubility water‚ ethanol.
Purity min. 99.5%.

TLC [CHCl3-MeOH-NH3 25% (10:10:1)‚ Rf=0.90‚ Sulifol]; 13C NMR (D2O)
Optical Activity
Toxicity (LD50) mice (orally): ~1 358 mg/kg.
Chemical Names 3-ethoxycarbonylquinuclidine hydrochloride.
Storage & Reconstitution Recommendations store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 9.13 ml)‚ stable for 1-2 days at 20°C.
Safety Recommendations do not swallow; avoid extra-large quantity inhalation.
 
Bibliographic References
  1. Burkin et al., Khim. Farm. Zh. (1992). (5):12-13
  2. Ziatzeva, Farm. Toxikol (1972) (Russian). 35(6):153-155
  3. Sharapov I.V., Farm, Toksikol. (1972). (Russian). 25(6):695-698
 
Prices
Code
Quantity
US $
€uro
L9064
1 x 2 mg
96.60
69.00
5 x 2 mg
386.40
276.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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