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Home Page > Alphabetical Index > PEMPIDONE

PEMPIDONE Prod. No L9067 - CAS # 94167-76-7
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Product Name PEMPIDONE
(Syn.: PMP=O)
Product Code L9067
PEMPIDONE

C10H19NO .HI
Molecular Formula C10H19NO .HI
Description

Nicotinic receptor antagonist; ganglioblocker; good penetration of biological membranes.

Piperidine derivative‚ C10H19NO .HI ‚ synthetic.
 
Biological Activity

Non-quaternary ganglioblocker‚ less potent than Pempidine and Tempidine [1-3].
Good penetration of biological membranes.

For detailed information see the 3 attached tables.
 
Chemical and Physical Properties
 
CAS No. 94167-76-7 Molecular Weight 297.17 Da.
RTECS Physical Form colorless crystals.
Merck Index No (13th Ed.) Melting point 195-197 °C.
PubChem SID Solubility well in water and ethanol.
Purity min. 98%. Optical Activity
Toxicity (LD50) mice (orally): 200-230 mg/kg.
Chemical Names 1‚2‚2‚6‚6-pentamethylpiperidone hydroiodide.
Storage & Reconstitution Recommendations Stable when kept dry‚ store in a dark place‚ at room temperature. Solution for use: 10-3 M
Safety Recommendations Do not swallow nor inhale; avoid eyes and skin contact.
 
Bibliographic References
  1. Brehteric et al., Nature (1959). 184:1707-1709
  2. Lutz et al., J. Org. Chem. (1962) 27(5):1695-1703
  3. Philippot E. et al., Arch. Int. Pharmacodyn. Ther. (1962). 135(3-4):273-280
 
Prices
Code
Quantity
US $
€uro
L9067
5 mg
81.20
58.00
25 mg
324.80
232.00
 
External Links PubMed Biomedical Citations From PubMed Toxicology Citations From PubMed PubChem SID

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