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Home Page > Alphabetical Index > NICARDIPINE HCl
| NICARDIPINE HCl Prod. No L9069 - CAS # 54527-84-3 |
| Product Name | NICARDIPINE HCl (Syn.: YC-93 HCl Nicodel Perdipine) |
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| Product Code | L9069 | ![]() C26H29N3O6.HCl |
| Molecular Formula | C26H29N3O6.HCl | |
| Description | a L-type Ca2+ channels blocker; antihypertensive. Dihydropyridine derivative C26H29N3O6.HCl synthetic. |
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| Biological Activity | Inhibits L-type Ca2+ channels in chick sensory neurons [4]. |
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| Chemical and Physical Properties | |||||||||||||||
| CAS No. | 54527-84-3 | Molecular Weight | 516 Da. | ||||||||||||
| RTECS | Physical Form | light yellow solid. | |||||||||||||
| Merck Index No (13th Ed.) | 6403 | Melting point | 168-170 °C. | ||||||||||||
| PubChem SID | Solubility | in dilute aqueous alkaline solution and chloroform-methanol (1:1); not in water. | |||||||||||||
| Purity | min. 99%. (TLC) | Optical Activity | |||||||||||||
| Toxicity (LD50) | rat (orally): 187 mg/kg; rat (i.v.): 15.5 mg/kg; mice (orally): 322 mg/kg; mice (i.v.): 19.9 mg/kg. rat (i.p.): 155 mg/kg; rat (s.c.): 683 mg/kg; mice (i.p.): 123 mg/kg; mice (s.c.): 540 mg/kg. |
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| Chemical Names | 14-Dihydro-26-dimethyl-4-(3-nitrophenyl)-35-pyridinedicarboxylic acid methyl 2- [methyl-(phenylmethyl)amino]ethyl ester hydrochloride. | ||||||||||||||
| Storage & Reconstitution Recommendations | stable when kept dry; store at room temperature in a dark place. | ||||||||||||||
| Safety Recommendations | do not inhale nor swallow prevent contact with skin. | ||||||||||||||
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